Example sentences of "significant change in [art] [noun] " in BNC.

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1 A very significant change in the towns of the First or Old Temple Period was the development of the temples as major craft centres .
2 These Proposals represent a significant change in the character of community nursing , not least the effective phasing out of specific specialist community job titles such as district nurse and health visitor .
3 The previous 1991 order was discussed at a slightly later time of night , but on the same day of the week nine months ago , since when there has been no significant change in the construction industry 's circumstances .
4 The methodology represents a significant change in the development of computing systems away from the technology , in particular , hardware and software ( including programming techniques and algorithms ) , and towards data and the way it is structured .
5 The Cabinet reshuffle reflected little significant change in the policies of Roh Tae Woo , although some observers considered it indicative of his desire to make greater efforts to sustain and develop the recent dialogue with North Korea .
6 There was no significant change in the propagation velocity after healing of oesophagitis ( 3.3 v 3.3 cm/second ( Fig 5 ) .
7 During the 1970s there was no significant change in the level of health education and the real price of cigarettes was if anything falling .
8 But heating and housing technology were not brought to bear on this , the single most significant change in the way we live .
9 There was no significant change in the patient 's height , weight , or body mass index during the study ( Table I ) .
10 The most significant change in the government , to which most ministers were reappointed , albeit with altered responsibilities , was the replacement of Mohamed Said Abdallah Mchangama , Djohar 's son-in-law , by Kandi Ali Ashtotosi , a new appointment , as Minister of Finance , Budget , Economy , Commerce and Planning .
11 Scientists have pointed to the collapse of the shrimp catch and a sharp decline in the number of mangrove trees along the Saudi shoreline as evidence of a significant change in the ecosystem .
12 There will no longer be a requirement to include an accountant 's report in listing particulars or circulars unless there has been a significant change in the company 's financial position within the last three financial years , or its accounts in any of those three years have been qualified .
13 Over the past year we have seen a significant change in the Company 's shareholder base with approximately 13 per cent of our shares now held by US investors .
14 There was no significant change in the durations of contraction after the healing of oesophagitis ( 3.1 v 3.1 ; 3.0 v 3.0 ; 2.8 v 2.5 seconds for the distal , middle , and proximal oesophagus respectively ) .
15 The 1980s have seen a significant change in the fortunes of the major executive search firms in London .
16 The 19th century had witnessed a significant change in the distribution and occupations of the population .
17 But now , rather like recording afresh over the existing programme on an audio or visual cassette , Sylvia had superimposed a successful situation and had thereby made a significant change in the data recognized by her subconscious .
18 Many of the genes in a family might have to be converted to a new variant before any significant change in the phenotype occurs-but by that time all individuals would have a similar proportion of the new variant and so would be physically very similar .
19 Between 1963 and 1965 the volcano Irazu in Costa Rica was more or less continuously active , with frequent explosions raining ash over a wide area and ruining the all-important coffee crop , but throughout this time no lavas were erupted and there was no significant change in the pattern of the eruption .
20 If there is a significant change in the pattern of flows at one point , it is quite likely that this will cause further changes in contingent flows .
21 There was no significant change in the median lower oesophageal sphincter pressure after healing of oesophagitis ( 16.5 v 20 mm Hg after healing ( Fig 3 ) ) .
22 When bFGF was administered subcutaneously or by intragastric route in a dose of 100 µg/kg , there was no significant change in the ethanol induced gastric lesions .
23 Following such treatment , there was a significant change in the numbers of these organisms in the patients ' bowels and this change could last for many weeks or months , during which time the patient continued to improve .
24 The average number of BrdU-labelled oligodendrocyte precursor cells fell by 80% in the TTX-treated nerve , but there was no significant change in the numbers of BrdU-labelled cells in the remaining population , indicating that TTX specifically blocks proliferation of the oligodendrocyte precursor cells ( Fig. 2b ) .
25 However , in 1982 , the World Health Organization stated that there was little likelihood of a significant change in the ozone layer in this century as a result of changing agricultural practices , but that the topic requires further study because of possible long-term effects ( Hulm , 1982 ) .
26 The change procedure is bypassed if he considers that the change is beneficial and that no significant change in the functionality of the relevant sub-system , or impact on the development schedule , will be incurred .
27 The US Federal Trade Commission 's investigation of Microsoft Corp has had an air of unreality about it , with few people imagining that it will come to anything very much or lead to any significant change in the market , but now that the thing may be coming to a climax , what are the possible outcomes ?
28 There had been no significant change in the interim nor any change in the local authority 's proposed future management .
29 Accompanying these changes in the balance of provider roles was a significant change in the kinds of accommodation provided .
30 It recommended an increase in IMF resources , significant changes in the conditions attached to IMF loans and more emphasis on supply factors ( resource utilisation ) rather than reducing demand in crisis-hit LDCs .
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