Example sentences of "of [noun] led [prep] the " in BNC.

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1 Their discovery helped overthrow the medieval concept of the Solar System and a few decades later , by a method that I shall not describe , observations of Io led to the first determination of the speed of light , which until then was thought by many philosophers to be infinite .
2 His pernickety attitude and lack of experience led to the film going almost 100 per cent over-budget .
3 Strong public pressure opposed to the scheme and lack of funds led to the decision .
4 The first of these lines of research led to the development of so-called creativity tests in which the subject has a free hand to generate his or her own responses to a given problem .
5 Iraq 's invasion of Kuwait led to the abandonment by the UAE of a traditional policy of neutrality and to a welcome for the deployment of the military forces of the US-led coalition in the region .
6 However , the possibility that hydrogen atoms could undergo fusion reactions and produce large amounts of neutrons led to the work being classified in 1951 .
7 The patchwork quilt of administrative decision-making powers reinforced the idea that this was not a new system of law in the making and the formalism of normativism led to the idea that to the extent that we had administrative law , the subject consisted wholly or mainly of delegated legislation and administrative adjudication ; that is , the forms of administrative action classifiable in terms of a conception of a formal separation of powers .
8 The growth of bureaucracy led to the proliferation of officials with functions as police , tax collectors and customs officers who might have had their offices in such places .
9 Unions became registered , thereby conferring access to an arbitration tribunal , and once registered they were largely protected from the emergence of new , rival organisations.8 As a result , the system of registration led to the early establishment and subsequent continuation of a large number of small unions and , as a secondary consequence , helped to impede amalgamation and union rationalisation .
10 From a therapeutic aspect , penicillin was marvellous because it cured many dangerous bacterial infections , but it was tiresome because it was inactive by mouth ( it was destroyed by the acidity of the stomach contents ) , it acted for a very short time ( it was rapidly excreted by the kidneys ) and so was of little value unless given by injection at intervals of not longer than 3 hours , and because , after a time , the normal processes of evolution led to the appearance of resistant strains of the microbes which had previously been sensitive to penicillin .
11 A reappraisal of resources led to the closing of the Southern Region centre and concentration at Portland Place .
12 In September a combination of politically clean hands plus a rising tide of Bonapartism led to the Prince 's being elected yet again , this time in five separate constituencies .
13 However , the industrial growth which took place throughout France changed the traditional patterns of work in Paris as elsewhere , and the introduction of machinery led to the establishment in the city of sugar refining , dyeing , and — around the railway yards — engineering .
14 Shortage of timber led to the increased planting of fast growing conifers such as Norway spruce .
15 This incident , despite having nothing to do with the operation of tribunals led to the establishment in 1955 of the Committee on Administrative Tribunals and Enquiries under the chairmanship of Sir Oliver Franks ( as he then was ) .
16 The need for more flexibility and economy of operation led to the rebuilding of 725 with new ends and a front entrance/exit in 1979 .
17 His concern about the evil effects of drunkenness led to the formation of the Langley Temperance Club , and he was also active in the social work of the Church of England .
18 If one man would pay generously to become Nawab , then so would another , and the attraction of gifts paid out upon a change of ruler led to the deposition of three Nawabs in rapid succession , which reduced the position to one which was obviously that of a puppet of the Company .
19 A succession of marquees led to the fairground complex , dominated by a great ferris wheel .
20 So the death of Crossroads led to the start of perfect partnership .
21 In the 1970s , this kind of pressure led to the prevalence of an increasing pool of funds allocated to soft or mixed commercial credits , which some EC governments were able to describe as aid .
22 The ostensibly matriarchal society of Tehuantepec led to the adoption of the Tehuana , in post-revolutionary Mexico , as the image of the strong Indian woman ; the undefeated counterpart to the despised ‘ Chingada ’ , who , conversely is the female embodiment of Mexico 's hybrid post-conquest culture .
23 Incubation with therapeutic concentrations of drugs led to the following reductions in binding : 10 mM 5ASA , 20% ( p<0.001 ) ; 10 mM N-acetyl-5ASA , 24% ( p<0.01 ) ; 10 mM 4ASA , 21% ( p<0.005 ) ; 10 mM N-acetyl-4ASA , 29% ( p<0.001 ) ; and 1 mM olsalazine , 29% ( p<0.001 ) .
24 It was put there in 1982 after a series of strikes led to the airline being shut down .
25 In July 1980 a dispute at the Lenin shipyards in the Baltic port of Gdansk led to the formation of an inter-strike committee and shortly afterwards to the establishment of Solidarity , the first ( and so far the last ) genuinely self-governing trade union that has ever existed in a communist-ruled country .
26 The experimental study of heredity led to the emergence of genetics , while ecology was presented as an extension of physiology into the study of the organism 's reaction to its environment .
27 The experimental approach to the study of heredity led to the creation of the new science of genetics .
28 Comparison with teaching in a traditional classroom course of the same length of time led to the use of CAI for all the SCORPIO training .
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