Example sentences of "is know [that] [noun] " in BNC.

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1 How comforting it is to know that Charles can communicate so well with people who are 40 or 50 years older than himself .
2 For example , it is know that leukotrienes are potent chemotactic compounds .
3 ( It is known that performance deteriorates after several hours of work. ) 3 .
4 It is known that sampling is used very little , and when it is used , is often used incorrectly .
5 It is known that changes in temperature or ionic strength alter the average rotation angle between adjacent base pairs in the DNA helix which , in a closed-circular DNA , leads to a change in the superhelical density ( 20 ) .
6 It is known that ATBC gets into food when the film is in direct contact , and migration increases when temperatures are raised .
7 It is known that youths grew their hair long in preparation for a ritual offering of a lock of hair to the deity .
8 If it is known that behaviour depends smoothly , and the second derivative of the dependence is never zero and its first derivative is bounded away from zero , then the Newton-Raphson method is better .
9 Little is known about how and why these last two conditions are helped , but it is known that protection against osteoporosis lasts only as long as the treatment is taken .
10 The majority were German Shepherds but it is known that Rottweilers did contribute .
11 It is known that Rottweilers had been imported prior to the Second World War , probably by German and Dutch immigrants .
12 It is known that St. Leonard 's Priory had some academic function , for in the fourteenth century it was partly used as a study centre for young monks , possibly preparing them for their degree courses at Oxford .
13 Some studies have used marks on shells that would disappear if shells decrease in size ; it is known that molluscs can remain living for long periods without detectable growth ; and some studies have recorded negative growth but dismissed it as apparent error .
14 It concluded ‘ that there would be little trouble in finding someone to take up the unassigned bonds when it is known that bonds in Sunningdale and other golf links have increased nearly 50% since their issue ’ .
15 Although it is known that plasma concentrations of both peptides increase in response to feeding , the mechanism by which ingested food causes release of colonic hormones is not understood .
16 It is known that Dionysos was worshipped at Pylos shortly after the Minoan period on Crete and it is possible that his orgiastic cult was preceded by a Minoan proto-Dionysian cult .
17 It is known that Freemantle criticized ‘ An Essay on Woman ’ when it was written ; apart from concerns with Leapor 's penmanship , it seems that she objected to the description of a miser and the reflections on wealth which follow .
18 It is known that Edward III another great royal builder , compared Westminster favourably with the apocryphal resting-place of the Three Kings at Cologne .
19 It is known that rainforest destruction threatens the well-being of the environment .
20 It is known that attacks on plants by herbivores reduce the quality of the tissues for subsequent feeding .
21 It is known that 70% of PSC patients have coexisting ulcerative colitis , and about 5% of ulcerative colitis patients develop PSC .
22 It is known that Aymer was in France in 1299 , 1301 , 1302 , 1303 , 1304 , and made at least twelve visits between 1307 and 1324 , three of them in 1313 .
23 It is known that phosphorylation of the c-Jun A1 activation domain increases transcriptional activity of the protein ( 13 , 14 ) ; perhaps phosphorylation of Ser-249 has a similar effect on the A2 domain ( amino acid residues 238-257 ; ref. 29 ) .
24 Dr Pertwee says the receptors are found in the brain areas where it is known that cannabis acts to produce many of its effects .
25 Very often , if it is known that additions will be made precisely evenly throughout the file , it will also be known when they will be made .
26 It may be that this goddess was worshipped at the peak sanctuaries , where it is known that pyres were lit ; the later Artemis cult also involved mountain-top bonfires .
27 It has often been said that the family kept the process secret , but this seems unlikely , since it is known that pearl ash was used to secure the transparency .
28 It is known that dogs of herding and hunting ability were already in north Switzerland and south Germany , an area once known as Helvetia .
29 Perhaps as a result of Syrian influence , companies of eunuch priests may have inhabited the Minoan temples ; in a later period , it is known that eunuch priests served Cybele and Attis in Anatolia .
30 It is known that SCAMP cost £3 million but no one will say what percentage of that figure is public money .
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