Example sentences of "with barrett ['s] " in BNC.

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1 The severity of oesophagitis in patients with Barrett 's oesophagus was classified in the same way as in other patients and depended on the endoscopic appearance of the oesophageal mucosa above the neosquamocolumnar junction .
2 Hiatus hernia was absent in only one of the nine patients with Barrett 's oesophagus .
3 These results were confirmed when patients with Barrett 's oesophagus were compared separately as a group with patients without Barrett 's oesophagus using the Mann-Whitney U test .
4 Patients with Barrett 's oesophagus tended to have significantly longer median oesophageal transit times in supine posture ( 180 v 13.5 seconds ; p=0.0004 ) but there was no difference in the erect posture .
5 Patients with Barrett 's oesophagus also had significantly lower median lower oesophageal sphincter pressures ( 9.5 v 17 mm Hg ; p=0.014 ) but there was no difference in any of the other manometric parameters .
6 The number of patients with Barrett 's oesophagus who had an acid clearance test was too small ( three ) to make any valid comparisons with the patients without Barrett 's oesophagus .
7 Although endoscopic surveillance and biopsy are performed to achieve an early diagnosis of malignant degeneration , many patients with Barrett 's oesophagus present primarily with symptoms of an oesophageal carcinoma .
8 The reported mean age of patients with an adenocarcinoma associated with Barrett 's oesophagus is about 57 years and the male to female ratio is 5.5:1 .
9 While most patients with an adenocarcinoma associated with Barrett 's oesophagus are resectable , the long term survival is low .
10 In patients with Barrett 's columnar lined oesophagus , specimens were also taken from the gastric cardia for comparison .
11 The 20 patients with Barrett 's mucosa showed abnormal expression of EGF in 25% of the isthmus and superficial epithelial cells .
12 Patient 's with Barrett 's mucosa had three specimens taken from the area of columnar lined oesophagus and a fourth from the gastric cardia for comparison .
13 On histological examination , five of the subjects with Barrett 's mucosa had moderate or high grade dysplasia , while the other 15 had no dysplasia .
14 No patient with an intact fundic wrap seen on endoscopy , only two of seven with Barrett 's oesophagus , and one of four with abnormal reflux had oesophagitis .
15 At follow up abnormal oesophageal mucosa was seen in eight patients , all with corresponding histology ( Fig 4 ) , and including two cases of grade 2 oesophagitis , one of them concomitant with Barrett 's oesophagus .
16 On the other hand , most patients with Barrett 's oesophagus had defective fundic wrap and most of the cases with objectively seen reflux were in this group .
17 The slight increase of residual activity associated with Barrett 's oesophagus may have been partly a result of the uptake of isotype by the Barrett mucosa , and this residual activity did not interfere with calculation of the transit indices .
18 Patients with Barrett 's columnar lined lower oesophagus have severe acid gastrooesophageal reflux and may develop complications , including ulceration , stricture , and carcinoma .
19 The aim of this study was to establish if a relationship exists between the pH profile in the oesophagus and stomach and the development of complications in patients with Barrett 's columnar lined lower oesophagus .
20 Twenty four hour ambulatory oesophageal pH monitoring was performed in 26 patients with Barrett 's columnar lined lower oesophagus and combined with 24 hour ambulatory gastric pH monitoring in 16 .
21 Ten of the 26 with Barrett 's columnar lined lower oesophagus had complications including stricture ( eight ) , deep ulceration ( one ) , and carcinoma ( one ) .
22 Such complications occur in approximately 50% of patients with Barrett 's columnar lined lower oesophagus .
23 It is well recognised that patients with Barrett 's columnar lined lower oesophagus represent the worst end of the reflux spectrum with the most severe forms of lower oesophageal sphincter and pump failure and consequently greater degrees of acid exposure .
24 Increased oesophageal alkaline exposure has been previously demonstrated in patients with Barrett 's columnar lined lower oesophagus and it has been suggested that this might be secondary to increased duodenogastric reflux using discriminant analysis in a small number of patients .
25 The aim of this study was , first , to measure the pH profile in the lower oesophagus of patients with Barrett 's oesophagus and by simultaneous ambulatory oesophageal and gastric pH monitoring , to correlate any alterations with changes in gastric pH .
26 Twenty six patients with Barrett 's columnar lined lower oesophagus were diagnosed by endoscopic documentation of the squamocolumnar junction being circumferentially more than 3 cm above the endoscopically determined anatomical oesophagogastric junction .
27 The duration of exposure of the lower oesophagus to acid in patients with Barrett 's columnar lined lower oesophagus is illustrated in Figure 2 , and shows that both groups had markedly increased acid exposure ( % total time pH <4= 19.2 ( 5.1 ) % v 19.3 ( 4.9 ) % ) , in comparison with asymptomatic controls .
28 Oesophageal motility studies showed that 16 of the 26 patients with Barrett 's columnar lined lower oesophagus had a defective lower oesophageal sphincter as defined by Zaninotto et al and a similar proportion of each group had weak or ineffective lower oesophageal peristaltic amplitude .
29 This study confirms that patients with Barrett 's columnar lined lower oesophagus have a marked degree of acid gastrooesophageal reflux , considerably exceeding that seen in the majority of patients with erosive oesophagitis without columnarisation .
30 This supports the findings of a previous study which described increased oesophageal alkaline exposure in patients with Barrett 's oesophagus .
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