Example sentences of "the nucleation time " in BNC.
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| 1 | In the present study the addition of increasing doses of egg lecithin to human and model biles progressively prolongs the nucleation time . |
| 2 | These and other variations in phospholipid molecular species shifted cholesterol among its carriers and also modified the nucleation time of model biles . |
| 3 | Similar amounts of bile salts did not prolong the nucleation time . |
| 4 | In the present study we have analysed the effect of various phospholipids and different molecular species of lecithin on cholesterol distribution between its carriers in bile and their effect on the nucleation time . |
| 5 | The Student 's paired t test was used to compare the nucleation time experiments , the per cent of cholesterol in the vesicular phase and the cholesterol/phospholipid ratios of nature biles after the addition of phospholipids . |
| 6 | Figure 3 shows the effect of the addition of egg lecithin on the nucleation time of seven human biles . |
| 7 | Increasing amounts of egg lecithin progressively prolonged the nucleation time . |
| 8 | After the addition of 1 µmol/ml of lecithin , the nucleation time was lengthened in only one bile and after 2.5 µmol/ml in only two biles . |
| 9 | After 5 µmol/ml the nucleation time increased considerably in five of seven biles ( p<0.05 ) . |
| 10 | In order to investigate the effect of different phospholipids on cholesterol solubility and the nucleation time we chose three synthetic phospholipids with an identical fatty acid composition but different head groups ( see methods ) . |
| 11 | The nucleation time of these model biles was also markedly affected by the variation in phospholipid species ( Table II ) . |
| 12 | The nucleation time of the model biles prepared with the different phospholipids are shown in Table II . |
| 13 | Model biles prepared with phosphatidylcholine , containing different fatty acids , had the following nucleation times : when both fatty acids ( sn-1 and sn-2 ) were saturated ( Palmitic and stearic ) the nucleation time was prolonged ( 20 days ) in comparison with other phosphatidylcholines containing one unsaturated fatty acid in the sn-2 position . |
| 14 | The results of this study show that the amount of phospholipids and their molecular species in bile have a decisive influence on cholesterol carriers , on the distribution of cholesterol among the carriers and on the nucleation time of bile . |
| 15 | The addition of similar amounts of bile salts with an equal effect on the cholesterol saturation index had no effect on the nucleation time . |
| 16 | They added 1.25 and 2.5 µmol of lecithin/ml bile while we added 5 µmol/ml bile , yet the prolongation in the nucleation time of bile was much more marked in their experiments . |
| 17 | The nucleation time was prolonged from 1.5 days to 12.2 and 13.2 days after the addition 2.5 µmol of synthetic lecithins . |
| 18 | In our experiments the nucleation time was considerably less prolonged ( Fig 5 ) . |
| 19 | As seen in Table II these disaturated synthetic lecithins prolonged the nucleation time to 20 days as compared with four to six days with the monosaturated lecithins . |
| 20 | When a similar shift is caused by the addition of bile salts or free fatty acids to bile the result is a shortening of the nucleation time . |
| 21 | Phospholipids , however , prolong the nucleation time . |
| 22 | An increase in the cholesterol/ phospholipids ratio has a very potent nucleating effect and shortens the nucleation time of model and human biles , whereas a decrease in the cholesterol/phospholipids ratio has an opposite effect . |
| 23 | Thus the addition of phosphatidylcholine prolonged the nucleation time by two mechanisms : ( A ) shift of biliary cholesterol to the more stable carrier ( non-vesicular ) and ( B ) a decrease in the cholesterol/phospholipids ratio of the metastable carrier ( vesicles ) . |
| 24 | The nucleation time of model biles was also markedly affected by varying the added phospholipid species . |
| 25 | When the acyl group composition was constant and the head group was varied the nucleation time was short with phosphatidylcholine and phosphatidylethanolamine and longer with phosphatidylserine . |
| 26 | One possible interpretation is that the nucleation time can be prolonged under two different circumstances : ( 1 ) When most of the cholesterol is in the more stable carrier(s) ( the non vesicular ) ; ( 2 ) When the metastable carrier is stabilised by a more rigid membrane ( disaturated phosphatidylcholine ) as well as a lower cholesterol/ phospholipids ratio ( which always occurs when most of the lipid is found in the vesicles ) . |
| 27 | The nucleation time in the hepatic bile of patients with cholesterol gall stones was significantly shorter than the gall stone free patients ( 8.2 ( 7.2 ) v 15.7 ( 5.8 ) days , p<0.05 ) , and was associated with a greater concentration of biliary lipid despite the lack of a difference in the cholesterol saturation index ( CSI ) and total protein concentration . |
| 28 | during the storage of bile in the gall bladder , the nucleation time became quicker in the patients with cholesterol gall stone ( 2.9 ( 1.7 ) days ) while it was similar in the gall stone free patients ( 17.3 ( 5.7 ) days ) compared with that of the corresponding hepatic bile . |
| 29 | Furthermore , despire a possible difference in the cholesterol metastability of hepatic bile between the patients with choesterol gall stones and control subjects , the nucleation time in hepatic bile has not been compared . |
| 30 | To examine the hypothesis , we verified the nucleation time , biliary lipid concentration , biliary protein concentration , and the distribution of vesicular cholesterol in paired hepatic and ball bladder bile from patients with or without cholesterol gall stones . |