Example sentences of "dose of [num] [unc] " in BNC.

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1 Similarly , in obese patients receiving weight reduction , Broomfield and colleagues found that in a dose of 1300 mg/day , aspirin inhibited ( albeit to a non-significant extent ) the development of microcrystals , microstones , and gall stones — which developed with high frequency in untreated patients .
2 To assess the effect of SOD and catalase , recombinant human Cu , Zn-SOD ( Nippon Kayaky Co , Ltd , Tokyo ) at a dose of 50000 U/kg , or catalase from bovine liver ( Sigma Chemical Co , St Louis , MO ) at a dose of 90000 U/kg dissolved in 1 ml of pphysiological saline , or both were injected subcutaneously one hour before and three hours after giving indomethacin .
3 In a randomised study of 84 patients , octreotide , given in a dose of 100 µg intravenously immediately before ERCP and subcutaneously 45 minutes later , significantly increased the incidence of pancreatitis from 11% ( control group ) to 35% ( octreotide group ) .
4 These were ( 1 ) vehicle ( saline ) given by intragastric instillation or subcutaneous infusion followed 30 minutes later by ulcerogen ; ( 2 ) bFGF infused subcutaneously in a dose of 100 µg/kg/hour followed 30 minutes later by ulcerogen ; ( 3 ) bFGF given by an intragastric route at a dose of 100 µg/kg followed 30 minutes later by ulcerogen , ( 4 ) sucralfate ( 100 mg/kg by intragastric instillation ) followed 30 minutes later by ulcerogen , ( 5 ) bFGF infused subcutaneously in a dose of 100 µg/kg/hour and sucralfate ( 100 mg/kg by intragastric instillation ) followed 30 minutes later by ulcerogen ; and ( 6 ) intragastric bFGF ( 100 µg/ kg ) given in combination with sucralfate ( 100 mg/kg ) followed 30 minutes later by ulcerogen .
5 When bFGF was administered subcutaneously or by intragastric route in a dose of 100 µg/kg , there was no significant change in the ethanol induced gastric lesions .
6 These were ( 1 ) vehicle ( saline ) given by intragastric instillation or subcutaneous infusion followed 30 minutes later by ulcerogen ; ( 2 ) bFGF infused subcutaneously in a dose of 100 µg/kg/hour followed 30 minutes later by ulcerogen ; ( 3 ) bFGF given by an intragastric route at a dose of 100 µg/kg followed 30 minutes later by ulcerogen , ( 4 ) sucralfate ( 100 mg/kg by intragastric instillation ) followed 30 minutes later by ulcerogen , ( 5 ) bFGF infused subcutaneously in a dose of 100 µg/kg/hour and sucralfate ( 100 mg/kg by intragastric instillation ) followed 30 minutes later by ulcerogen ; and ( 6 ) intragastric bFGF ( 100 µg/ kg ) given in combination with sucralfate ( 100 mg/kg ) followed 30 minutes later by ulcerogen .
7 These were ( 1 ) vehicle ( saline ) given by intragastric instillation or subcutaneous infusion followed 30 minutes later by ulcerogen ; ( 2 ) bFGF infused subcutaneously in a dose of 100 µg/kg/hour followed 30 minutes later by ulcerogen ; ( 3 ) bFGF given by an intragastric route at a dose of 100 µg/kg followed 30 minutes later by ulcerogen , ( 4 ) sucralfate ( 100 mg/kg by intragastric instillation ) followed 30 minutes later by ulcerogen , ( 5 ) bFGF infused subcutaneously in a dose of 100 µg/kg/hour and sucralfate ( 100 mg/kg by intragastric instillation ) followed 30 minutes later by ulcerogen ; and ( 6 ) intragastric bFGF ( 100 µg/ kg ) given in combination with sucralfate ( 100 mg/kg ) followed 30 minutes later by ulcerogen .
8 One hour before being killed , each rat received H-thymidine through the internal jugular vein ( specific activity 20.0 Ci/ mmol , Du Pont de Nemours GmbH , Germany ) in a dose of 1 µCi/g body weight .
9 A dose of 5 µmol/l prostaglandin E 2 tested in our laboratory induced secretion of water , Na + and Cl - similar to 25 µg cholera toxin , but without affecting HCO 3 - absorption .
10 Ergocalciferol ( vitamin D 2 ) at a dose of 10 nM reduced CCPR in the normal rectal tissue from 5.27–2.74 cells/ crypt/hour .
11 After intravenous administration of a pulse dose of 10 µCi [ 1-C ] L-leucine , a four hour intravenous infusion consisting of 500 ml 0.45% sodium chloride , 50 µCi [ 1-C ] L-leucine tracer , secretin ( 2.0 Crick-Harper-Raper U/kg/ h ) , and cholecystokinin ( 0.5 CHR U/kg/h ) was started .
12 Pancreatitis was induced by caerulein that was diluted in saline and infused sc for five hours in conscious animals at a dose of 10 µg/kg/h and at a rate of 1 ml/h .
13 Subcutaneous infusion of caerulein at a dose of 10 µg/kg/h for five hours consistently produced pancreatitis in all tested rats .
14 In this study we also used the technique of continuous sc infusion of caerulein at a dose of 10 µg/kg/h for five hours and this resulted in the increase in the pancreatic weight and the morphological alterations of pancreatitis comparable with that reported by Robert et al .
15 We studied the effect of octreotide administered in a dose of 50 µg on the sphincter of Oddi using endoscopic manometry in seven patients and found that this hormone increase basal pressure and the frequency of phasic wave contractions appreciably ( submitted for publication ) .
16 Activity of SOD in serum reached a maximum of about 100 U/ml after 150 minutes when SOD was subcutaneously injected at a dose of 50000 U/kg .
17 To assess the effect of SOD and catalase , recombinant human Cu , Zn-SOD ( Nippon Kayaky Co , Ltd , Tokyo ) at a dose of 50000 U/kg , or catalase from bovine liver ( Sigma Chemical Co , St Louis , MO ) at a dose of 90000 U/kg dissolved in 1 ml of pphysiological saline , or both were injected subcutaneously one hour before and three hours after giving indomethacin .
18 The reduction in the ulcer area after treatment with intraperitoneal bFGF at a dose of 30 µg/kg/day was comparable with that obtained with omeprazole at a dose of 60 mg/kg/ day — namely , almost complete inhibition of gastric acid secretion ( Table II ) .
19 This early ‘ satiating effect ’ was dose dependent and most marked at a dose of 40 µg per animal ; about equimolar to procolipase secretion during maximal stimulation with secretin and cholecystokinin ( CCK ) .
20 This effect lasted up to four hours with a dose of 20 µg per animal but was prolonged for up to six hours with a dosage of 40–80 µg per animal .
21 A dose of 20 per cent less than the LD 50 will kill few and a dose of 20 per cent more will kill over 90 per cent ’ .
22 A dose of 20 per cent less than the LD 50 will kill few and a dose of 20 per cent more will kill over 90 per cent ’ .
23 In a randomised study of 16 patients with idiopathic recurrent pancreatitis who were undergoing hydrostatic balloon dilation of the pancreatic duct sphincter , somatostatin given intravenously at a dose of 250 µg/hour one hour before and 12 hours after dilatation reduced the incidence and severity of acute pancreatitis compared with placebo .
24 In a study of 56 patients randomised to somatostatin or placebo , somatostatin , administered in a dose of 250 µg/hour after contrast media emptying of the pancreatic duct , did not reduce hyperamylasaemia or pancreatitis like pain .
25 In a study of 54 patients undergoing endoscopic sphincterotomy , the continuous infusion of cyclic somatostatin in a dose of 250 µg/hour over 26 hours beginning two hours before ERCP did not significantly reduce pancreatic enzyme rise compared with placebo .
26 A study of 26 patients who received somatostatin in a dose of 250 µg/hour over 24 hours did not show significant reduction in amylase activities compared with historical controls .
27 A dose of 0.05 µg/kg body weight of ceruletide ( Farmitalia Carlo Erba Ltd , St Albans , UK ) in 10 ml saline was then given by intravenous injection over a 10 minute period .
28 In the first series of experiments on motor function of the ileocolonic junction , we studied the effects of ia saline , 5HT , and bethanechol chloride , at a dose of 3.05 mmol/kg ( Merck , Sharp , and Dohme , West Point , PA ) .
29 We found a maximum of fluid secretion of 88 ml/30 cm/h with a dose of 25 µg cholera toxin four hours after exposure to the toxin .
30 This study shows that the long acting somatostatin analogue SMS 201–995 given subcutaneously in a dose of 25 µg three times daily can abolish hypergastrinaemia induced by five days ' treatment with omeprazole ( 40 mg once daily in man .
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