Example sentences of "[pron] have be know [prep] " in BNC.

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31 It has been known for some time that eyes give out bioelectric signals — the retina has a positive charge , the cornea is negative .
32 For example , it is still commonplace in cartoons to show cavemen and dinosaurs together , despite the fact that it has been known for many years that dinosaurs were extinct long before the evolution of ‘ cavemen ’ .
33 It has been known for many years that rich clusters contain a lot of gas and dark matter , but Ponman and Bertram 's result shows that these features apply more generally .
34 It has been known for some time that the majority of fibres from the left and right eyes converge upon single cells in the visual cortex of the cat and monkey ( Hubel and Wiesel , 1967 ) .
35 It has been known for a long time that , partly due to their immense size , elephants can hear much lower sounds than we can .
36 It has been known for many years that neurons , like other cells , can be maintained alive and well under such conditions for periods of many days or even weeks , provided they are kept warm , aerated and well fed with glucose and other essential molecules .
37 Finally , they could sometimes be accused of deception and dishonesty — it has been known for reporters from The Independent to lobby the lobby .
38 It has been known for caterers to come in at 8am , turn all the ovens on and not use them for three hours . ’
39 Is not the Minister aware that it has been known for some time that four times as many women as men suffer the chronic pain that comes from the loss of movement in and the fracture of hip joints ?
40 It has been known for many years that recycling used materials helps make great savings , but it was not until recently that it was realised how much good that it could do for the environment .
41 It has been known for some time that the inactive form of ALDH2 is present in about 50% of Japanese and Chinese and is associated with high acetaldehyde concentrations , an exaggerated flush response to alcohol , and seems to protect against alcoholism .
42 It has been known for some time that versatile plastics could be made from vegetable matter but production costs have been prohibitive .
43 He says that it has been known for drugs to be smuggled in large packages .
44 It has been known for some time that the Inland Revenue has been taking a close interest in the marketing practices of livestock farmers in parts of Wales and the West Country .
45 It has been known for its medicinal properties for 2,000 years and has been used by Russian cosmonauts since the 1970s .
46 It has been known for developers to move in virtually overnight to demolish a building once they find out attempts are being made to list it .
47 It has been known to the West since the 17th century .
48 When a telephone is installed , it is possible to have a very long flex put on for very little extra cost , and it can then be carried to any room , but you should consider the advantages and disadvantages of this carefully before coming to a decision to have it done , as it has been known to be the cause of accidents to some old people .
49 That matter is not really as we perceive it has been known to chemists and physicists for over 150 years , but despite Einstein 's demonstration , and that of other atomic scientists since , that matter and energy are interchangeable , we persist in our view that physical matter is solid and stable .
50 It has been known to our people for centuries .
51 This should never happen , but it has been known to , and being safe rather than sorry is always best .
52 The evening meal is usually around seven , although it has been known to be at nine .
53 Although serious research on the subject of mobbing did not begin until around the time of the Second World War , it has been known as a natural phenomenon for over 2,500 years .
54 In fact it has been known since the late 1950s ( see for example Nature , vol. 208 , p 423 ) that Po is widely distributed in the environment , and in man , as a result of atmospheric fall-out of the decay products of natural radon-222 , with an abundance in northern temperate latitudes of about 0.06 curie per sq.km or of the order of 10 6 curies in total over the surface of the world land mass .
55 It has been known since the 1970s that the vehicles which have dramatically increased our mobility in the last 50 years have also constituted a grave danger .
56 Composers do not seem to have found much use for this device , though it has been known since Weber 's day .
57 It had been known for a long time that histamine was responsible for producing many allergies and the first antihistamine drug was produced in France in 1937 .
58 It had been known for some time that relations between Stephenson and Villa were strained because of the player 's insistence on living in his home-town of Newcastle , and several clubs , keen to secure him , were watching the situation closely .
59 At one time so many people from the area were hanged at Newgate it had been nicknamed Jack Ketch 's Warren , and according to Paddy it had been known for as many as forty constables to march down with cutlasses to control disturbances .
60 By the time of Fritz and Hitzig 's work it had been known for nearly a century that electrical stimulation of nervous tissue would produce movements .
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