Example sentences of "[adj] [adv] significant [noun sg] in " in BNC.

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1 Many clients can become frustrated by this fact , believing that there must be some very significant detail in their past which has caused them to become anxious or stressed currently .
2 But heating and housing technology were not brought to bear on this , the single most significant change in the way we live .
3 In short , the single most significant factor in the unemployed status of those who had previously worked had been their use of heroin .
4 The single most significant feature in this landscape was the Labour Party .
5 The rate of secretion in both groups fell by 25% without any statistically significant change in pyloric loss or duodenogastric reflux .
6 Perhaps the other highly significant change in Sussex agriculture to have affected birds is the more recent and extensive drainage of the important areas of wet permanent pasture in the river valleys and levels , which amount to some 16,000 hectares .
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