Example sentences of "[vb -s] [prep] a large " in BNC.

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1 When iron is released the protein goes through a large conformational change involving domain rotation and exposure of the empty metal-binding site to the solvent .
2 A muffin tin looks like a large , deep bun tray .
3 ‘ Well , it looks like a large dog , look at its head . ’
4 Yeah , it looks like a large family group .
5 This develops into a large bulky plant 2ft high , which collapses after heavy frost , blanketing the ground and breaking down into a mass of fibre .
6 To my mind the only possibility of solving this problem lies in a large European prospective randomised screening study comparing screening with no screening and using mortality from prostatic cancer as its major end point .
7 Within easy reach of the town centre and on a frequent bus route , Wexford House stands in a large garden which will afford a pleasant area for future residents .
8 Within each reach of the town centre and on a frequent bus route , Wexford House stands in a large garden which will afford a pleasant area for future residents .
9 She lives in a large , sunny and specially adapted local authority bungalow in Northampton : the walls of the living room are decorated with her paintings ( done when she still had some use of her right hand ) and her kitchen cupboard is covered with postcards , love letters from old boyfriends and local newspaper articles .
10 He lives in a large house near here . ’
11 He lives in a large provincial town with his second partner Beth , their small son Henry , and Alice , his teenage daughter by a previous marriage .
12 Cross-border banking is essentially wholesale banking and has to a large extent been dependent on euro-currency deposit growth .
13 The overall response of the British state to this twofold crisis has to a large extent been characterized by penological pragmatism : responding to developments and attempting to manage the resources crisis ‘ with no clear or coherent philosophical or other theoretical basis ’ ( Bottoms , 1990a : 4 ) .
14 Fortunately continuing research by agrochemical manufacturers has to a large extent enabled the persistent organo-chlorides to be suspended .
15 ‘ Traditional climatic geomorphology as represented by most of the papers in this volume has to a large extent glossed over this paucity of knowledge of fundamentals ; it may be said to have proceeded , like Davis 's work , to premature generalization on the basis of quite vague ideas on the underlying process relations .
16 For a continuously varying trait ( let us use human size as an example ) , the value of the trait in an individual is probably determined by what genes it has at a large number of genetic loci , together with the effect of the environment .
17 ‘ I take anything the Major says with a large pinch of salt , ’ she said crisply .
18 It begins gently at first , a pipe bridge , a lattice canal footbridge and an arched cable bridge , and then develops in earnest as sliproads flail through the air , the M6 crosses , the Birmingham to Lichfield railway passes through and ever more sliproads arc over until the canal passes into a large box tunnel with two towpaths below the A38M Aston Expressway before emerging into the relative simplicity of Salford Junction below the M6 .
19 This results in a larger tax burden on the properties scale A to E to pay , for a reduced burden on the scales F to H.
20 In numerical terms , the nursing workforce renews itself every six years which results in a large population of nurses who are not practising within the NHS .
21 The credibility of alternatives depends in a large measure on three factors : a new perspective on disruption and disaffection ; support for teachers ; a re-alignment of current resources .
22 The key word then features in a large illustration for the child to colour in .
23 Having no involvement with the GPC rules , it is a faster process , but it depends upon a large sight vocabulary .
24 This breakpoint probably occurs within a large block of simple sequence satellite III DNA located close to the centromere ( 34 ) .
25 All these matters were basically concerned with the maintenance of acceptable standards of safety and it is only fair to acknowledge the fact that the high standard of safety in public transport aircraft today results to a large extent from work done by ICAO .
26 How far the glider rolls over into the beginning of the spin depends to a large extent on the amount of yaw present .
27 Obviously what is helpful and what is unhelpful depends to a large extent on the circumstances of the situation .
28 Its versatility depends to a large extent upon its structure , a knowledge of which is vital if we are to make the best use of glass .
29 With cereal-based foods , fibre value depends to a large degree on how much has been stripped away in the milling and refining processes .
30 The rate of fire decay behind the flame front depends to a large extent on fire loading , the physical state and thermal capacity of the fuel and does not appear to have been studied in the same depth .
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