Example sentences of "[noun] activating [noun] " in BNC.
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| 1 | This study was performed in an attempt to estimate the mucosal activity of neutrophils in ulcerative colitis and elucidate the possible neutrophil activating role certain cytokines may exert . |
| 2 | The release of myeloperoxidase correlated to an enhanced local release of the neutrophil activating peptide interleukin 8 ( IL-8 ) . |
| 3 | Human neutrophil activating peptide/interleukin 8 ( NAP-1/ IL-8 ) is a single , non-glycosylated peptide chain ; its main activities include activation and chemotactic attraction of neutrophils . |
| 4 | Plasminogen activating activity was significantly lower in malignant ascites ( n=10 , median <0.02 ( range <0.02–1.26 ) IU/ml ) than in alcoholic ascites ( n=10 , 1.07 ( 0.30–1.49 ) IU/ml ) ( p<0.05 ) . |
| 5 | The plasminogen activating activity of alcohol ascites may lead to primary fibrinolysis after peritoneovenous shunting . |
| 6 | This has been confirmed by direct measurement of ascitic plasminogen activating activity and has led to speculation that an infusion of plasminogen activators could stimulate a coagulopathy mediated by primary fibrinolysis . |
| 7 | Plasminogen activating activity was determined by the fibrin plate method after incubation for 24 hours at 37°C and the results expressed as IU tissue polasminogen activator/ ml ascitic fluid ( lower limit of detection 0.02 IU/ ml ) . |
| 8 | The plasminogen activating activity was significating higher in alcoholic cirrhotic ascites ( median 1.07 ( range 0.30–1.49 ) IU/ml ) than in malignant ascites ( <0.02 ( <0.02–1.26 ) IU/ml , p<0.05 ) . |
| 9 | There was no positive correlation between the plasminogen activating activity and the severity of alcoholic liver disease in the cirrhotic group , based on serum albumin ( r = 0.04 ) , bilirubin ( r =0.45 ) , or prothrombin time ( r =0.24 ) . |
| 10 | Our results confirm that alcoholic ascites contains plasminogen activating activity . |
| 11 | These studies show that the plasminogen activating activity of ascites is primarily mediated by tissue plasminogen activator and that it is also probably responsible for a coagulopathy mediated by primary fibrinolysis after insertion of a peritoneovenous shunt . |
| 12 | As a control the K562 blot was also probed with a β-globin probe to show the presence of the locus activating region hypersensitive sites ( data not shown , 42 ) . |
| 13 | The transcriptional regulatory sequences of carcinoembryonic antigen ( implicated in colorectal cancer ) , tyrosinase ( melanoma ) , c-erb B2 ( breast , pancreatic , and gastric cancer ) , and α fetoprotein ( hepatoma ) have been coupled to the genes for several drug activating enzymes . |
| 14 | Role of platelet activating factor on the fibrinolytic activation in the pathogenesis of gastric mucosal damage induced by endothelin-1 |
| 15 | We determined tissue type plasminogen activator activity in the regional blood sample and the concentration of platelet activating factor in the gastric mucosa after the administration of endothelin-1 in a range of 50–500 pmol/ kg into the left gastric artery of male Wistar rats . |
| 16 | Endothelin-1 increased the tissue type plasminogen activator release and platelet activating factor formation , and induced subsequent gastric mucosal haemorrhagic change in a dose dependent manner . |
| 17 | In addition CV-6209 , a selective platelet activating factor blocker , attenuated the activation of regional tissue type plasminogen activator and the development of mucosal damage induced by endothelin-1 . |
| 18 | The results of this study showed that tissue type plasminogen activator activation may play an important role in the pathogenesis of endothelin induced mucosal injury of rat stomach , and suggest that the platelet activating factor may be involved in the process of regional fibrinolytic activation induced by endothelin-1 . |
| 19 | A previous study has shown that mucosal tissue type plasminogen activator , when released from endothelial cells by platelet activating factor , plays an important role in the process of gastric ulcer formation by inducing macromolecular permeable change in the rat experimental model . |
| 20 | In addition we have also investigated the involvement of platelet activating factor in the endothelin induced fibrinolytic activation . |
| 21 | The level of platelet activating factor in the rat gastric mucosa was determined after the administration of endothelin-1 using a radioimmunoassay method . |
| 22 | Total lipids of mucosal homogenate of rat antrum were extracted by the method of Bligh and Dyer at 4°C in the presence of 50 mM glycine HCl buffer ( pH 2.8 ) in a one phase system to inactivate platelet activating factor acetylhydolase . |
| 23 | The chloroform layer , which contains the purified lipid extract , was isolated and used to determine the platelet activating factor concentration , using the platelet activating factor [ H ] scintillation proximity assay system purchased from Amersham International plc ( UK ) . |
| 24 | The chloroform layer , which contains the purified lipid extract , was isolated and used to determine the platelet activating factor concentration , using the platelet activating factor [ H ] scintillation proximity assay system purchased from Amersham International plc ( UK ) . |
| 25 | The assay system is based on the competition between unlabelled platelet activating factor and a fixed quantity of [ H ] labelled platelet activating factor for a limited number of binding sites on a platelet activating factor specific antibody . |
| 26 | The assay system is based on the competition between unlabelled platelet activating factor and a fixed quantity of [ H ] labelled platelet activating factor for a limited number of binding sites on a platelet activating factor specific antibody . |
| 27 | The assay system is based on the competition between unlabelled platelet activating factor and a fixed quantity of [ H ] labelled platelet activating factor for a limited number of binding sites on a platelet activating factor specific antibody . |
| 28 | The platelet activating factor concentration of mucosa from rat antrum was expressed as pmol/g frozen tissue . |
| 29 | To assess the involvement of platelet activating factor in the endothelin induced tissue type plasminogen activator activation in gastric mucosa , CV-6209 ( a gift from Takeda Pharm Co ) , a selective platelet activating factor blocker , was intravenously administered at a dose of 0.001–0.1 mg/kg five minutes before the injection of endothelin-1 . |
| 30 | To assess the involvement of platelet activating factor in the endothelin induced tissue type plasminogen activator activation in gastric mucosa , CV-6209 ( a gift from Takeda Pharm Co ) , a selective platelet activating factor blocker , was intravenously administered at a dose of 0.001–0.1 mg/kg five minutes before the injection of endothelin-1 . |