Example sentences of "it is know that [noun] [prep] " in BNC.
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| 1 | It concluded ‘ that there would be little trouble in finding someone to take up the unassigned bonds when it is known that bonds in Sunningdale and other golf links have increased nearly 50% since their issue ’ . |
| 2 | Little is known about how and why these last two conditions are helped , but it is known that protection against osteoporosis lasts only as long as the treatment is taken . |
| 3 | It is known that changes in temperature or ionic strength alter the average rotation angle between adjacent base pairs in the DNA helix which , in a closed-circular DNA , leads to a change in the superhelical density ( 20 ) . |
| 4 | It is known that 70% of PSC patients have coexisting ulcerative colitis , and about 5% of ulcerative colitis patients develop PSC . |
| 5 | It is known that phosphorylation of the c-Jun A1 activation domain increases transcriptional activity of the protein ( 13 , 14 ) ; perhaps phosphorylation of Ser-249 has a similar effect on the A2 domain ( amino acid residues 238-257 ; ref. 29 ) . |
| 6 | It is known that dogs of herding and hunting ability were already in north Switzerland and south Germany , an area once known as Helvetia . |
| 7 | It is known that myelinisation of the fibres of the corpus callosum is not complete until about 10 years of age ( Yakovlev and Lecours , 1967 ) . |
| 8 | It is known that attacks on plants by herbivores reduce the quality of the tissues for subsequent feeding . |