Example sentences of "make a significant [noun sg] " in BNC.

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1 The individual teacher may well have made a significant development in his or her own understanding , but that is not a sufficient condition of securing publication ( thesis three ) .
2 No-one has yet made a significant case for inclusion .
3 Now scientists working at the John Radcliffe Hospital in Oxford believe they 've made a significant discovery in how asthma is passed down the family tree .
4 Take heart : the green consumer movement has made a significant dent in manufacturing practices over a very short time .
5 THE RUC has made a significant breakthrough against a large IRA killer squad operating in North Belfast .
6 Doctors believe they 've made a significant breakthrough in the fight against one of Britain 's fastest growing illnesses .
7 Thus , as Table 5 demonstrates , the teams were the principal vehicle for residential developments in the social services department and also made a significant contribution to such activity in the voluntary sector .
8 If the Union had made a significant contribution to solving health problems , it had also unquestionably played a more significant role in awakening community action .
9 Founded in 1977 by art collector , philanthropist and businessman Jan Mitchell , the prize is awarded to authors of new books which have made a significant contribution to the study and understanding of the visual arts .
10 The Whitney Museum of American Art has established an honorary award to be given annually ‘ to an individual or representatives of an organisation who have made a significant contribution to the arts in America through a sustained commitment to the diversity , quality and originality of American artistic achievement ’ .
11 On the other hand , if tomorrow I confirm a speculative theory implying that the gravitational attraction between two bodies depends on their temperature , falsifying Newton 's theory in the process , I would have made a significant contribution to scientific knowledge .
12 Lastly , the ‘ joint venture ’ vessels , which were principally affected by the Act of 1988 , had made a significant contribution to the economic and social development of Milford Haven .
13 He might have made a significant contribution to the public life of this country had he not been totally overshadowed by his illustrious father and had he not had such a burning desire to shine as bright or even brighter .
14 Paracelsus therefore made a significant contribution to medical knowledge across a broad front .
15 Nor could he avoid reminding Charlotte of the hopeful turn Colin 's case had taken — a turn to which she had made a significant contribution — while her niece 's plight seemed only to worsen by the day .
16 The 5/ a week given in 1908 to those aged over seventy would have made a significant contribution to the pre-war family economy , but the Standing Joint Committee of Industrial Women 's Organisations and members of the Fabian Women 's Group felt that this should be weighed against the increased friction caused by an old person coming into an already overcrowded home , pointing out that elderly people 's ideas of hygiene and childrearing might not be desirable , an argument that appealed to the infant welfare movement .
17 The unanimous condemnation of marriage as a trade by the feminist movement may also have made a significant contribution to the new emphasis on marriage as a partnership .
18 Already the computer has made a significant contribution to the processing of much of the routine data generated by office staff .
19 The GASB ( 1990 ) has made a significant contribution to the problems of defining the reporting entity .
20 Retiring chairman Phillipa Burrow told the Association 's annual dinner at Torquay that Packard had made a significant contribution , both regionally and nationally , to the Association 's educational , training and personal development issues .
21 It will also take account of the successful introduction of DROPS — the demountable rack offloading and pickup system — which has made a significant contribution to the capability of the Royal Corps of Transport , given the quantity of stores that can be shifted with the available resources .
22 The acquisition in October 1992 of The Alta Group Inc. , a leading supplier of high purity titanium , has made a significant contribution to operating profit .
23 Publication in a high-impact factor journal such as Nature represents an acknowledgment that the work is at the cutting edge of science , and that it has made a significant contribution to that science .
24 His energy and enthusiasm have already made a significant contribution to the style and driving forward of the many issues with which the Association is involved .
25 Provision of a range of safety equipment for Marathon and new Solas standard life jackets for Chevron also made a significant contribution to the company 's business .
26 NOW entering its third year , Teesside Training and Enterprise Council has already made a significant contribution to the social and economic life of the region .
27 Neither made a significant provision before 1820 , and their rivalry still persisted in the 1830s when the government began at last to assist them with grants .
28 But now , rather like recording afresh over the existing programme on an audio or visual cassette , Sylvia had superimposed a successful situation and had thereby made a significant change in the data recognized by her subconscious .
29 Whether this input has made a significant impact on the pattern of activity is a moot point .
30 The overwhelming consensus amongst respondents was that microcomputers had made a significant impact on their organizations .
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