Example sentences of "[verb] a significant [noun] " in BNC.

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1 The upshot of all this is that takeovers involve a significant degree of risk for offerors .
2 All projects involve a significant element of software development .
3 they usually involve a significant part of the work being carried out without close supervision ;
4 Thus exposure to FGF-4 causes a significant increase in the number of cells initiating DNA synthesis .
5 The isolated DNA binding domain of HSV-1 Vmw175 causes a significant DNA bend in the immediate vicinity of the Vmw175 binding sequence spanning the HSV-1 IE-3 mRNA start site ( 26 ) .
6 This remains unknown in man , but we have investigated the effects of commonly used anaesthetic agents on tissue protein synthesis in the rat and found that although halothane causes a significant depression of liver protein synthesis , isoflurance did not have such an effect .
7 We conclude that acute cigarette smoking causes a significant fall in gastric secretion ( Vg ) , and suggest that this results in raised gastrin values that have a tropic effect on the parietal cell , thereby accounting for the raised secretory capacity of chronic smokers .
8 When the Kruskall-Wallis test disclosed a significant p value , the Mann-Whitney U test was carried out in order to detect where the differences occur .
9 Imports of computer equipment manufactured in the European Community are subject to lower rates of duty , but have not won a significant share of the local market .
10 Nevertheless , Noriega 's attorneys had previously won a significant victory : on Aug. 8 presiding US District Court judge William Hoeveler ruled against the Justice and State departments and the Central Intelligence Agency ( CIA ) that the defence should have access to classified government documents concerning the relationship between US intelligence agencies and the accused .
11 The government saw chena cultivation as a threat to the state 's right to forest land , a matter of some importance because the sale of Crown land provided a significant proportion of official revenue in the nineteenth century .
12 The revenue from arrack and toddy provided a significant portion of official income , as did the salt monopoly , railway receipts and income from the commutation of an annual labour levy on adult men .
13 However , both also suggest a significant influence absent both from Middleborough and the Lion and Stag pavement .
14 Both estimates suggest a significant increase in the numbers of elderly with chronic health problems in the early decades of next century .
15 A company is treated as an associated undertaking when the group holds a substantial interest in it for the long term , and exercises a significant influence over its operating and financial policy decisions .
16 The salt business is highly profitable ( £91m on $466m sales in 1991 , representing a significant proportion of the company 's pretax profits of £214m ) and provides much of the cash for growth .
17 The answer , quite simply , is that other port employees are now allocated to dock work , representing a significant change to both working practices and labour utilisation .
18 Towards the end of 1992 Draught Guinness was launched in Sweden , representing a significant breakthrough for the import of foreign draught beers .
19 After the First World War the term ‘ regional planning ’ was used extensively , the new practice representing a significant extension to planning practice .
20 A parallel-group study with 24 children given half the dose of evening primrose oil that we used for 4 weeks , demonstrated a significant difference between active and placebo groups , a finding that we can not explain .
21 Overcrowding is becoming a significant problem with the explosion in mobile communications and broadcasting services .
22 Continental crust is only about one-half as efficient at conducting heat as oceanic crust , so if a supercontinent , such as Pangaea , covers a significant part of the Earth 's surface heat will build up in the mantle below it .
23 Nowadays , too , the suggestion that a woman 's role consists entirely of slaving over the cooker , the kitchen sink and the washing is certain to irritate a significant number of people , though it is still a real enough situation for the majority of women .
24 Erm the resident population will of course er include a significant proportion of people who are migrating into the district er as we saw last week .
25 Furthermore to insist that a procedure must include a significant element of external control could hinder the implementation of remedies : a criticism which is often regarded as the most important .
26 Expected to comprise some 3,000 lots , the art , accumulated in the late 1950s and 1960s , will include a significant amount of good quality if not exactly highly refined eighteenth-century French furniture .
27 The inter-war working-class holiday organizations had occupied a significant place , gradually introducing a previously untravelled sector of the population to the educative and recreative value of foreign travel while yet accommodating a more traditional pattern of holiday-making .
28 This was based on the 1975 white paper which proposed a significant increase in home food production to reduce dependence on imports which had risen sharply in cost .
29 In written recommendations presented on July 24 Boutros-Ghali proposed a significant strengthening of the UN operation in Somalia , with a UN presence to be established throughout the country .
30 One thing , at any rate , would seem to be clear , and this is that Jesus , after his baptism in the Jordan , undergoes a significant change .
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