Example sentences of "[adv] [adv prt] [noun pl] " in BNC.

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1 ‘ Slowly , but very deliberately , the brooding edifice of seduction , creaking and incongruous , came into being , a vast Heath Robinson mechanism , dually controlled by us and lumbering gloomily down vistas of triteness .
2 Council housing is becoming more and more marginalised as the better off tenants move out and higher rents encourage others to exercise their right to buy .
3 WOMEN on low incomes were more than twice as likely to smoke as their better off counterparts , claims a new report out today .
4 Like a lot of old slang words from you know like a hun fifty or so back years ago are now proper words now .
5 Single channel recordings were obtained from membrane patches in cell attached and excised inside out configurations as described previously .
6 With high K + solution in the bath , cell membrane voltage was assumed to be zero , and V c o m was therefore equivalent to the potential across the membrane patch in both the cell attached and inside out configurations .
7 The event , organised by Tony Hoffman of Inside Out Promotions , brought together the four major winners of the NTTC season , namely the Masters champion , Yorkshire 's Paul Robinson , Classic champion , Nick Baglin , from SKF Matchpoint , Alverstoke 's Darren Quilty , the hardcourt winner and John Black , representing Breakpoint Mizuno , who is the official No. 1 ranked player .
8 Nick toasts his sponsors Tim Garland ( centre ) and Tony Hoffman ( Inside Out Promotions )
9 High conductance ( about 155 pS ) K channels were active spontaneously in 17% of cell attached or excised inside out patches in non-stimulated subconfluent HGT-1 cells .
10 In inside out patches , channel activity increased fivefold during depolarisation , ion substitution experiments confirmed that the channels were highly selective for K , and channel activity was almost abolished by removal of Ca 2 or addition of 5 mM Ba .
11 In some experiments with inside out patches , single channel recordings were obtained after replacing the high K + solution with a low K + solution containing ( mM ) : K + , 22.5 ; Na + , 122.5 ; Cl - , 149 ; Ca 2 + , 1.2 ; Mg 2 + , 1.2 ; glucose 10 ; and HEPES 10 , titrated to pH 7.4 with NaOH .
12 The sensitivity of K + channels to Ca 2 + ions was determined in excised inside out patches by recording ( V c o m =0 mV ) first in the presence of the Ca 2 + containing high K + bath solution , and then in the presence of a Ca 2 + free high K + solution containing the Ca 2 + chelator ethyleneglycol-bis ( Β -aminoethyl ether ) N , N' tetra-acetic acid ( EGTA , 5 mM ) .
13 Under basal conditions , spontaneous channel activity was seen at V c o m =0 mV in 6 of 35 ( 17% ) cell attached patches and in 14 of 85 ( 16% ) excised inside out patches .
14 One channel was seen in three of the six cell attached patches and in six of 14 inside out patches , while two or three channels were active simultaneously in the other patches .
15 K + channel activity was also studied over a range of pipette potentials in a series of excised inside out patches , and Fig 2A shows results from a patch that contained a single channel ( high K + bath solution , NaCl pipette solution ) .
16 The mean values of g - 4 , E r e v , and P K : P N a ratio from 14 inside out patches were 62 ( 6 ) pS , 153 ( 11 ) pS , -84.8 ( 0.1 ) mV and 260 ( 11 ) : 1 respectively , and were not significantly different from those obtained in the cell attached configuration .
17 Figure 2B shows smaller outward K + currents across one of four inside out patches when the K + concentration of the bath solution was decreased from 145 mM to 22.5 mM ( with equimolar Na + replacement ) , and Fig 2C shows the effect of this change in bath K + concentration on the I-V c o m curves for the channel .
18 Figure 3 shows the relation between single channel open probability ( P o ) and pipette potential ( V c o m ) in excised inside out patches ( high K + bath solution , NaCl pipette solution ) .
19 In contrast , with inside out patches ( for example , Fig 2A ) channels generally spent longer in the open state at equivalent values of V c o m , while closed times were similar to those seen in cell attached patches ( see below ) .
20 Figure 4B shows histograms from one of five inside out patches , which again showed ( at V c o m =0 mV ) one open time constant ( mean value 31.1 ( 10.0 ) ms ) and two closed time constants ( mean values 0.4 ( 0.1 ) ms and 1.8 ( 0.3 ) ms ) , with mean open and closed times of 30.4 ( 8.1 ) ms and 1.5 ( 0.2 ) ms respectively .
21 It should be noted that the mean open time was significantly longer and the mean closed time was significantly shorter in the inside out patches than in the cell attached patches ( 30.4 ( 8.1 ) ms v 6.8 ( 0.7 ) ms , p<0.05 and 1.5 ( 0.2 ) ms v 3.0 ( 0.5 ) ms , p<0.05 respectively ) .
22 To determine the Ca 2 + sensitivity of K + channels in inside out patches , recordings were attempted after the Ca 2 + containing ( 1.2 mM ) high K + bath solution was replaced with either a Ca 2 + free high K + solution containing 5 mM EGTA ( Ca 2 + concentration 10 nM ) or an EGTA buffered high K + solution containing 1 µM Ca 2 + .
23 Consequently , Ca 2 + sensitivity of the K + channel was examined in only two inside out patches at V c o m =0 mV .
24 The effect Ba 2 + ions ( final bath concentration 5 mM ) on K + channel activity was examined in inside out patches ( V c o m =0 mV ) .
25 As mentioned above , it was not possible to perform a detailed study of the Ca 2 + sensitivity of K + channels in excised inside out patches .
26 We saw K + channel activity in 17% of cell attached and inside out patches from HGT-1 cells in the absence of acid secretory agonists .
27 I must have been mad on the strength of one fish , going all out boilies but it was a double and I just had a feeling this was how the better fish might fall .
28 A dozen of us were waiting in Out Patients , all with something wrong down there , in an area designated ‘ the water works ’ .
29 That day was not a V.V.C. day in Out Patients and , in any event , as it was after six o'clock , Out Patients had closed .
30 Our Hi-Tech business continues to progress well , with growth in both portfolio and profits , and this is a great tribute to the all round skills of the two managers , Sylvia Hume and Jan Brien .
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