Example sentences of "been [verb] have [art] [adj] effect " in BNC.

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1 In the fourth phase of progress , population-based antenatal screening — maternal serum alpha fetoprotein and ultrasound screening , sometimes complemented by amniocentesis — has been proven to have a substantial effect .
2 While most of us would acknowledge that some level of stress is required to enable us to function and to be sufficiently motivated , the effects of continued high levels of stress have been shown to have a damaging effect on the ability to maintain our personal sense of purpose , usefulness and well-being .
3 One has been shown to have a direct effect on killing cancer cells while leaving normal cells unharmed .
4 Dairy products , most notably cheese , have been shown to have an inflammatory effect on scalp conditions .
5 The gastrointestinal hormone cholecystokinine has been shown to have an opposite effect on the human sphincter of Oddi compared with that of the rabbit and prairie dog .
6 In fact , their campaign and the probably well-founded suspicion that the result had been rigged had the opposite effect .
7 In some situations , such as providing purely factual information , this may be the case , but insensitive memos have been known to have an adverse effect on the motivation of others and their willingness to carry out instructions .
8 The obese diabetic ( Ideal body weight > 120 per cent : Metropolitan Life Insurance Company , 1959 ) must be encouraged to lose weight as this has been found to have a blood-pressure-lowering effect which may or may not be related to concomitant reduction of dietary sodium ( Reisin et al , 1978 ; Tuck et al , 1981 ; Fagerberg et al , 1984 ) .
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