Example sentences of "and has led [prep] [art] [noun] " in BNC.
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| 1 | The development of flexible endoscopy , which allows pancolonic biopsy , has supported this finding and has led to a change in practice such that in many centres at risk patients are examined at intervals , with colonoscopy and biopsy , to detect premalignant dysplasia or early cancer . |
| 2 | The notion that Germany possesses some magical formula for everlasting material success is deep-rooted and has led to a string of further propositions . |
| 3 | The initial agreement covers many capital goods ( excluding informatics ) and has led to an increase in trade and specialisation . |
| 4 | The most obvious result of such ‘ cuts ’ has been to affect most adversely those without any other pension provision , and has led to an increase in the numbers claiming means-tested support . |
| 5 | This pioneering work continues in Oxford and has led to the discovery that in sheep the heart-rate of the unborn lamb can be accurately measured ; it varies with the health of the mother , and in particular with the oxygen in the mother 's blood stream . |
| 6 | This situation makes it difficult to use basal colonic motility as a basis for comparisons and has led to the development of provocation tests in a controlled environment in an attempt to characterise differences between groups of patients . |
| 7 | All this second-generation old school stuff is shite on wheels and has led to the emergence of the Old School Fool , a mug with a large disposable income who is prepared to cough up half a week 's wages for anything he perceives to be pre-Day-Glo sportswear . |
| 8 | This combined with the smell of their droppings and the musky odour of the birds themselves , makes such colonies very smelly places and has led to the suggestion that the birds may use the smell to guide themselves back to it through the darkness of night . |
| 9 | v. Morgan [ 1985 ] A.C. 686. ( iii ) Unless undue influence or misrepresentation of the nature envisaged under ( i ) has in fact occurred , and has led to the execution of the document in question by the surety , again equity will not intervene , on that account . |
| 10 | That problem was recognised last year and has led to the introduction of the year-long pilot project which is to be the subject of independent monitoring . |
| 11 | Absorption or wet scrubbing as it is often called has however the disadvantage of having to dispose of the liquid effluent obtained , which may itself require treatment before disposal , and has led to the comment that we may be merely replacing one effluent problem by another by using this method . |
| 12 | Dominated , not monopolized : the obvious physical impressiveness of the remains in the city , and its consequent attraction for archaeologists , can easily lead , and has led in the past , to a neglect of the deme , the local population centre . |