Example sentences of "have become a major [noun sg] [noun] " in BNC.

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1 A second team is currently working at Moscow airport , which has become a major transit point for people without proper documents .
2 Palestinian stubbornness has become a major stumbling block to the peace process as conceived by the United States .
3 Endothelin-1 has become a major research topic since its discovery and characterisation as a potent vasoconstrictor .
4 Bush appeared to have recovered from what was later described as gastric influenza by the following day , but this was the second occasion within a year that the health of the 67-year-old President — and the possible succession of Vice-President Dan Quayle — had become a major news issue [ see p. 38183 ] .
5 State family planning programmes were first introduced in 1968 and since the establishment of the National Population Commission in 1974 , they have become a major government priority .
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